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Joined: 25 Aug 2013
Age: 64
Gender: Male
Posts: 25,956
Location: Long Island, New York

12 Jan 2021, 4:59 pm

Dopamine neurons may dampen social behavior in mouse model of autism

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons, according to a new study. Easing the overconnection may alleviate this trait, the researchers say.

Professionally Identified and joined WP August 26, 2013
DSM 5: Autism Spectrum Disorder, DSM IV: Aspergers Moderate Severity.

“My autism is not a superpower. It also isn’t some kind of god-forsaken, endless fountain of suffering inflicted on my family. It’s just part of who I am as a person”. - Sara Luterman


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Joined: 4 May 2020
Age: 19
Gender: Non-binary
Posts: 5,842
Location: Pacific Northwest

12 Jan 2021, 5:12 pm

Does this have an affect because the mice don't get "rewarded" as much by their brains for participating in social interaction? Sometimes I feel like my brain doesn't "reward" me for/derive pleasure from the type of interactions it should, so I don't seek them out as much.

I use he/him pronouns.

I like playing video games, watching cartoons and anime, reading, and cooking.

I have two cats, a rabbit, and a dog. I also enjoy learning + cataloguing information about different types of animals and plants.

Empathy Quotient: 34/80
Systemizing Quotient: 104/150
Friendship Quotient: 56/140
Autism Quotient: 36/80

RAADS-R: 169

CAT-Q: 153
Compensation: 57
Masking: 47
Assimilation: 49

Your broader autism cluster (Aspie) score: 144 of 200.
Your neurotypical (non-autistic) score: 63 of 200.
You are very likely on the broader autism cluster (Aspie).


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Joined: 17 Jul 2004
Age: 46
Gender: Male
Posts: 104,943
Location: Canada in person, Germany in spirit

12 Jan 2021, 11:12 pm

I saw the imaging. That's a very trippy image. I guess I have a very trippy brain.


Om Nom 2024



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Joined: 9 Jan 2021
Age: 99
Gender: Male
Posts: 252

13 Jan 2021, 12:22 pm

So it's that dopey dopamine 'o mine that's been causing all these problems.

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